- Hyperactive somatostatin interneurons contribute to excitotoxicity in
- Using TDP-43A315T mice, an ALS and FTD model with marked cortical pathology, we found that hyperactive somatostatin interneurons disinhibited layer 5 pyramidal neurons (L5-PNs) and contributed to their excitotoxicity. Focal ablation of somatostatin ...
- Treatment with a Ginkgo biloba extract, EGb 761, inhibits excitotoxicity in an
- Abstract: Spinocerebellar ataxia type 17 (SCA 17) is a polyglutamine disease caused by the expansion of CAG/CAA repeats in the TATA box-binding protein (TBP) gene. The Ginkgo biloba extract, EGb 761, contains flavonoids and terpenoids with a potential ...
- A Cortical Neuron Circuit Overloads in ALS Model Mice
- Excitotoxicity is a well-known culprit in the demise of motor neurons in ALS. In fact, the only FDA-approved treatment for the disease, riluzole, works by preventing the release of excess glutamate, which becomes excitotoxic.
- Exercise Benefits The Brain; Waste Product From Working Out Protects Neurons
- When one of these types of trauma occurs, a process called excitotoxicity is prompted.
- Antibiotics Underrecognized Cause of Delirium
- Antibiotic toxicity can represent an unrecognized cause of delirium in hospital patients, with manifestations observed in three distinct phenotypes, new research shows.
Excitotoxicity is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Excitotoxicity books and related discussion.
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