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Ribosome

Ribosome definition, a tiny, somewhat mitten-shaped organelle occurring in great numbers in the cell cytoplasm either freely, in small clusters, or attached to the ...

Ribosome is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Ribosome books and related discussion.

Suggested Pdf Resources

Structure and function of the ribosome - Nobelprize.org
Oct 7, 2009 Structure and function of the ribosome. This year's Nobel Prize in Chemistry is awarded to Venkatraman Ramakrishnan, Thomas A. Steitz and ...
Ribosome Profiling Enables Comprehensive Translation ... - Illumina
efficiency, such as mRNA splicing, ribosome pausing, and noncanoni- cal initiation. ... control influencing protein abundance, differences in ribosome density.
Atomic structures of the eukaryotic ribosome - Cell
structures of the small (40S) and large (60S) ribosomal subunits and the 80S ribosome now provide an atomic description of this essential molecular machine  ...
Ribosomes as Antibiotic Targets Ribosomes as ... - Lehigh University
The ribosome is the target of over 50% of existing antibacterial drugs. High resolution structures of bacterial ribosomal subunits offers new prospects for ...
The ribosome filter hypothesis
40S ribosomal subunits before translation may also selectively affect rates of ... According to the filter hypothesis, ribosome heterogeneity is expected to lead to ...

Suggested News Resources

Halting Ribosomal Rescue Key to Thwarting Virulent Bacteria
The general mechanism for most antibiotics is stopping microbial protein translation by stalling ribosomes on mRNA molecules. However, many bacteria have evolved rescue pathways that allow them to circumvent antibiotic mechanisms, helping to facilitate ...
Keeping ribosomes stuck may stop virulent bacteria strain in its track
Next Generation Antibiotics Could Protect Against Bioterrorism
The compounds target ribosomes in the translation phase of the bacteria's genetic process, he added. For bacteria to grow and proliferate, protein-generating ribosomes, like engines rolling down a track, must travel down the messenger RNA (mRNA) to ...
Motoring toward pre-60S-ribosome export
Rea1 is an ATPase related to dynein motor proteins that has been implicated in the biogenesis of the 60S ribosomal subunit. A new cryo-EM study vividly demonstrates the power of structural methods, deciphering the role of Rea1 in monitoring key pre-60S ...
Cotranslational protein folding on the ribosome monitored in real time
Proteins consist of linear chains of amino acids. These chains must fold into complex three-dimensional shapes to become functional. Holtkamp et al.

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