Serine Protease Zymogens
- Gap Junctions in Oncology Drug Pipeline Update 2015
- NEW YORK, July 20, 2015 /PRNewswire/ -- Gap junctions contain intercellular channels that allow direct communication between the cytosolic compartments of adjacent cells. Each gap junction channel is formed by docking of two 'hemichannels', each ...
- Alnylam Expands "Alnylam 5x15" RNAi Therapeutic Pipeline with ALN-APC
- Protein C is a serine protease blood coagulation factor that circulates as an inactive zymogen and is activated by thrombin during blood coagulation to form activated protein C (APC). APC is an endogenous anticoagulant that acts to reduce thrombin ...
- 苏州大学特聘教授Nature Medicine发表重要成
- Corin is a serine protease that activates the natriuretic peptides, thereby regulating blood pressure4. It is synthesized as a zymogen that is activated by proteolytic cleavage.
- Matriptase-2 is a hepatic membrane serine protease that regulates iron homeostasis. Defects in matriptase-2 cause iron deficiency anemia. In cells, matriptase-2 is synthesized as a zymogen.
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